Spontaneous resolution of Descemet membrane detachment following big-bubble deep anterior lamellar keratoplasty.

PURPOSE To report 2 cases of delayed spontaneous Descemet membrane (DM) reattachment following big-bubble deep anterior lamellar keratoplasty (DALK). METHODS A 21-year-old man with keratoconus and a 36-year-old woman with corneal macular dystrophy underwent big-bubble DALK. No injury to DM was noted intraoperatively or postoperatively. Postoperatively, the patients developed central DM detachment with double anterior chamber formation. A nonsurgical conservative approach (waiting technique) was adopted. RESULTS Three weeks postoperatively, the double anterior chamber resolved spontaneously with complete DM reattachment and a clear donor cornea. CONCLUSIONS DM detachment and double anterior chamber following big-bubble DALK may resolve spontaneously.